Tissue-based biomarkers in prostate cancer
نویسندگان
چکیده
منابع مشابه
Tissue Biomarkers for Prostate Cancer Radiation Therapy
Prostate cancer is the most common cancer and second leading cause of cancer deaths among men in the United States. Most men have localized disease diagnosed following an elevated serum prostate specific antigen test for cancer screening purposes. Standard treatment options consist of surgery or definitive radiation therapy directed by clinical factors that are organized into risk stratificatio...
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PURPOSE Prostate cancer is a bimodal disease with aggressive and indolent forms. Current prostate-specific-antigen testing and digital rectal examination screening provide ambiguous results leading to both under-and over-treatment. Accurate, consistent diagnosis is crucial to risk-stratify patients and facilitate clinical decision making as to treatment versus active surveillance. Diagnosis is ...
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Understanding the etiology of a disease such as prostate cancer may help in identifying populations at high risk, timely intervention of the disease, and proper treatment. Biomarkers, along with exposure history and clinical data, are useful tools to achieve these goals. Individual risk and population incidence of prostate cancer result from the intervention of genetic susceptibility and exposu...
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Localized prostate cancer (PCa) is a clinically heterogeneous disease, which presents with variability in patient outcomes within the same risk stratification (low, intermediate or high) and even within the same Gleason scores. Genomic tools have been developed with the purpose of stratifying patients affected by this disease to help physicians personalize therapies and follow-up schemes. This ...
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A n international team of researchers believe they may have found, if not the smoking gun, at least a few DNA “bullets” that determine whether prostate cancer will become aggressive. A new biomarker study, which appeared in the Aug. 16, 2011, online edition of Cancer Epidemiology, Biomarkers, and Prevention, identified five inherited genetic variants associated with aggressive prostate cancer. ...
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ژورنال
عنوان ژورنال: Expert Review of Precision Medicine and Drug Development
سال: 2017
ISSN: 2380-8993
DOI: 10.1080/23808993.2017.1372687